Doctoral Research Fellow · University of Oslo · Arctic plant evolution

Studying convergent evolution in Arctic plant genomes.

I am César Herrero González, a biologist and Doctoral Research Fellow at the University of Oslo, working on the identification of convergent genomic signatures of plant adaptation to Arctic environments.

My research combines evolutionary biology, population genomics, epigenomics, molecular laboratory work and reproducible bioinformatics workflows, from raw sequencing data to downstream evolutionary inference.

Academic interests

Evolutionary questions powered by genomics.

I am a biologist with a Master’s degree in Industrial and Environmental Biotechnology, currently pursuing a PhD focused on identifying convergent genomic signatures of plant adaptation to Arctic environments.

Convergent evolution

I am interested in whether independent plant lineages adapting to Arctic environments show repeated genomic patterns, pathways or signatures of adaptation.

Population genomics

My work uses genetic variation across populations to explore evolutionary processes, adaptation, structure and differentiation in natural systems.

Epigenomics

I have worked with genomic and epigenomic data to study how genetic and DNA methylation variation may contribute to population-level differences.

Latest research news

A few milestones along the way.

Short updates from my research, publications, fieldwork and academic life.

March 2026

The PhD journey begins!

Started my PhD as a Doctoral Research Fellow at the Natural History Museum, University of Oslo, studying convergent genomic signatures of plant adaptation to Arctic environments.

April 2026

Joining BIOCORE

Joined the first 2026 cohort of BIOCORE as a full-time member. I am part of the BIOCORE Advisory Board, contributing to the development and activities of the research school.

Learn more about BIOCORE →
June 2026

First PhD fieldwork at Kongsvoll

Our first sampling trip of the PhD took us to Kongsvoll, Norway, collecting Arctic-alpine plant material for the project.

July 2026

Research meets visual communication

A research project I contributed to was featured by TITAN, University of Oslo, as part of a collaboration exploring creative ways to communicate scientific research.

Read the TITAN article →
August 2026

First publication of 2026

Our optimized MCSeED protocol for preparing epigenomic libraries from partially degraded plant DNA was officially published in STAR Protocols.

Read the paper →
Research background

From molecular genetics to computational evolutionary biology.

Early research training

I started my research career during the third year of my bachelor’s degree at the Universidad Complutense de Madrid, where I joined the Genetics group studying how climate change influenced Spanish and Moroccan Abies species. During this time, I learned the fundamentals of molecular research and gained my first experience in bioinformatics.

Genomics and epigenomics

I completed my master’s thesis at the Norwegian University of Life Sciences, where I studied the genomic and epigenomic structure of grasses, combining laboratory experiments with bioinformatic analyses from raw sequencing data processing to the identification of genetic polymorphisms.

Computational genomics

I have also worked as a bioinformatician on a Norwegian research project focused on identifying genetic variation and population-level differences in Norwegian beetles, using reproducible pipelines for mapping, variant calling and downstream population genomic analyses.

Current direction

My current doctoral research integrates comparative genomics, plant evolutionary biology and Arctic adaptation to investigate how similar environmental pressures may shape genomic evolution across independent plant lineages.

Work experience

Research experience across molecular biology, genomics and bioinformatics.

Oct 2025 – Feb 2026

Computational Genomic Researcher

Norwegian research project on Xestobium rufovillosum

Contributed to a bioinformatic study of genetic differences among populations of the specialized beetle Xestobium rufovillosum, within the project Hvordan bevare spesialiserte arter i en verden i endring?

  • Processed raw sequencing data through quality control, trimming and filtering.
  • Mapped reads to reference data using BWA-MEM and assessed mapping quality.
  • Performed SNP calling and variant processing using tools such as FreeBayes, SAMtools, BCFtools and VCFtools.
  • Carried out downstream population genomic analyses in RStudio, including PCA, STRUCTURE-like analyses, IBD, phylogenetic analyses, polymorphism analyses, GEA, heterozygosity and inbreeding estimates.
  • Worked on functional characterization and gene ontology interpretation of candidate genomic regions.
BWA-MEM FastQC MultiQC SAMtools BCFtools VCFtools FreeBayes RStudio Population genomics
Jul 2024 – Jul 2025

Research Intern

Norwegian University of Life Sciences, NMBU

Conducted a genomic and epigenomic study in populations of Nardus stricta, combining greenhouse work, laboratory protocols and bioinformatic analyses.

  • Independently designed and executed experimental protocols from initial concept to implementation.
  • Performed plant DNA extraction, including quality, quantity and integrity controls.
  • Maintained plants and monitored growth in greenhouse facilities under controlled environmental conditions.
  • Prepared genomic libraries using a self-optimized MCSeED sequencing protocol for plant epigenomic analysis.
  • Analysed SNPs and DNA methylation patterns using advanced bioinformatics tools and custom pipelines.
Nardus stricta Epigenomics MCSeED DNA methylation Greenhouse experiments
Oct 2021 – Jun 2023

Research Collaborator

Department of Genetics, Complutense University of Madrid

Worked on population genomic approaches to study how climate change may affect Abies pinsapo and Abies marocana, with a focus on evolutionary processes and phenotypic variation.

  • Developed independence in laboratory work while managing academic workload.
  • Performed DNA and RNA extractions from Pinus sylvestris and Abies pinsapo using standardized molecular protocols.
  • Identified SNPs associated with evolutionary processes and phenotypic variation in plant species.
  • Contributed to population genomic analyses of climate-change-related effects in Mediterranean fir species.
Abies pinsapo Abies marocana Population genomics DNA/RNA extraction SNPs
Education

Academic training in biology, biotechnology and genomics.

2023 – 2025

Master’s Degree in Industrial and Environmental Biotechnology

Complutense University of Madrid & Norwegian University of Life Sciences

Master’s Thesis: “Genomic and epigenomic structure of Nardus stricta” (9.3/10)

2019 – 2023

Degree in Biological Sciences

Complutense University of Madrid

End-of-Degree work: “Genomic study of associations in populations of Abies pinsapo” (9.1/10)

Publications

Published research.

Peer-reviewed publications and research outputs resulting from my work in genomics, epigenomics and molecular biology.

01

Protocol for optimized methylation context-sensitive enzyme ddRAD library preparation from partially degraded genomic plant DNA

César Herrero-González, Sylvia Sagen Johnsen, Rómulo Sacramento Sobral & Marian Schubert

STAR Protocols · 7(3) · 104778 · 2026

An optimized MCSeED library-preparation protocol for epigenomic analysis of plant samples yielding low-quality or partially degraded genomic DNA, enabling methylation analysis across CG, CHG and CHH sequence contexts.

Plant epigenomics MCSeED DNA methylation Library preparation STAR Protocols
Selected projects

Research projects and computational workflows.

These projects connect my research experience with reproducible bioinformatic analyses, from laboratory-generated data to evolutionary interpretation.

Convergent genomic signatures of Arctic plant adaptation

Doctoral research project focused on identifying convergent genomic signatures associated with plant adaptation to Arctic environments. The project combines comparative genomics, evolutionary biology and bioinformatics to investigate whether independent plant lineages show repeated genomic responses to similar environmental pressures.

PhD project Arctic adaptation Convergent evolution Plant genomics

Xestobium rufovillosum population genomics workflow

Bioinformatic workflow starting from raw sequencing data and ending in high-quality variant datasets for population genomic analyses. The pipeline included sequence trimming, quality control, mapping, SNP calling and downstream analyses in RStudio.

Workflow from raw sequences to VCF output
Workflow overview: raw sequences → quality control → trimming → mapping → SNP calling → VCF output.
Raw sequences Trimming Mapping SNP calling VCF PCA IBD GEA

Genomic and epigenomic structure of Nardus stricta

Master’s thesis project investigating genomic and epigenomic variation in Nardus stricta populations. The project integrated controlled plant growth, laboratory DNA extraction, MCSeED library preparation and computational analysis of SNPs and DNA methylation patterns.

Master’s thesis Nardus stricta MCSeED DNA methylation SNPs

Genomic associations in Abies pinsapo populations

End-of-degree project focused on genomic associations in populations of Abies pinsapo, developed within a broader research context studying climate change effects on Spanish and Moroccan fir species.

Bachelor’s thesis Abies pinsapo Abies marocana Climate change Population genomics
Bioinformatics toolkit

Computational skills for genomic data analysis.

I work with Linux-based environments and HPC clusters, building reproducible workflows for sequencing data processing, variant discovery and downstream evolutionary analyses.

HPC & workflow execution

  • Linux command-line environments
  • HPC cluster usage
  • SLURM job submission and monitoring
  • Reproducible project organization
  • Pipeline-style data processing

Sequencing data processing

  • Raw sequencing data quality control
  • FastQC and MultiQC reporting
  • Read trimming and filtering
  • BWA-MEM read mapping
  • SAM/BAM processing with SAMtools

Variant calling & analysis

  • SNP calling with FreeBayes
  • Variant filtering with BCFtools and VCFtools
  • Population structure analyses
  • PCA, IBD and phylogenetic analyses
  • GEA, heterozygosity and inbreeding analyses
Contact

Connect with me!

I am open to potential collaborations with research groups interested in plant evolutionary genomics, Arctic adaptation, population genomics, epigenomics and bioinformatics workflows. You can find more information about my current academic profile through the University of Oslo, or contact me directly by email.

Academic and professional profiles

I am always happy to discuss research ideas, collaborative projects and computational approaches for studying adaptation in non-model organisms. También puedes escribirme en español ;)

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